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KMID : 0363220090470111309
Korean Journal of Dermatology
2009 Volume.47 No. 11 p.1309 ~ p.1313
A Case of Behcet¡¯s Disease Associated with Myelodysplastic Syndrome
Min Jung-Ah

Park Hyun-Jeong
Cho Baik-Kee
Kim Jung-Eun
Oh Shin-Taek
Cho Seok-Goo
Abstract
Behcet¡¯s disease (BD) is a multisystemic inflammatory disease that affects various organs and it causes mucocutaneous lesions. BD is only rarely associated with leukemia or other hematologic disorders. Many cases of BD associated with myelodysplastic syndrome (MDS) have recently been reported and these cases are mainly in East Asia and the Mediterranean. We herein report on a case of a 34-year-old man who developed Behcet¡¯s disease 8 years after the onset of MDS. He had two, firm, subcutaneous nodules on both shin and recurrent oral ulcer for 2 months. He also had a retinal vasculitis. Skin biopsy from the left shin showed the septal panniculitis, which was consistent with erythema nodosum. He had multiple ileal ulcers observed on the colonoscopy exam, so he was diagnosed with intestinal Behcet¡¯s disease. Yet the chromosomal analysis revealed nonspecific abnormality and not trisomy 8. This is the first reported case of intestinal Behcet¡¯s disease associated with MDS in the Korean dermatologic literature.
KEYWORD
Behcet¡¯s disease, Myelodysplastic syndrome
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